In the 2013 Shutdown, a number of government experiments (ie: Flu Experiments) were destroyed due to neglect from the shutdown. Which ended up having the worst Flu Vaccination success rate in the last 10 years or something (like a stupid low 30%).
Etc. etc. Government projects are stopped during shutdowns. It literally takes years to recover from a shutdown (another year or two before Flu Vaccination experiments were back up and running at full potential)