Life that is recognizable to us definitely needs some sort of solvent to even begin to exist. We know water can support life. We don't know that there are any other solvents that can. We also know of a bunch of places that don't have liquid water, like the moon, that don't appear to host life. Probably there isn't life on objects that look like the moon or Mercury.
Water is also really common (if not usually liquid), so you might expect that a good fraction of all the life in the universe would use water. Why worry about looking for exotic life in galactic nebulas (or whatever) when we aren't even sure how to detect it. Working out a way to detect watery life is way easier, and if there's a nearbyish exoplanet with a rocky Earthesque planet with water then we absolutely should look there first.