Not sure how VR solves the problem you describe. Your wife needs to be there in person if a skype call wouldn't suffice.
Modern VR headsets already have eye tracking, it's not too out of the picture to imagine some rudimentary face tracking to capture the rest of the foundations of expression. In my experience the sense of "thereness" is much greater in a VR room than a teleconferencing session; but it's difficult to compare since VR presupposes better audio conditions.
Her job description is basically investing several million dollars at a time into projects that a large number of participants in her industry (impact investing) believe are worthwhile, but no one fund would bankroll on its own. A key part of that job description is working to build partnerships & syndicates of investors whose goals are aligned. A key skill for that is building trust and rapport - the foundations, family offices, entrepreneurs, and hedge funds involved all need to feel like the deal is in their interest and they will be treated fairly, both if it goes well and if it goes poorly.
There's a bunch of social science that's shown that repeated in-person interaction builds trust in a way that e-mail, phone calls, written communication, and videoconferencing does not. It's not just the facial expression and emotions - there's something about interacting in real-time within a shared environment that makes us trust each other. And that's what I'm referring to by "good as there" telepresence - existing systems are not good enough, because there's still a big gulf between VCing with your coworker across the country and chatting with your officemate about a cool new opportunity. I don't know whether VR will ever be good enough to bridge this gulf, but I'm saying that if it can, that would be revolutionary.
If it were just a matter of deal terms & conditions, we could stick all that in a blockchain and let computers hash it out. That's my field, and I keep telling her that eventually the world'll move that way. But humans don't work that way; as long as we have squishy emotions and depend on a lot of subconscious cues we can't even describe, then looking at a screen is not going to change peoples' decision making. If you could somehow capture all those subconscious cues so it really is indistinguishable from physical presence, that may change, but that's a big if.