This article proposes raising levels of NAD to counter aging related dna damage.

My google search also resulted in: https://medicalxpress.com/news/2016-12-pathway-linked-slower...

TLDR; NAD+ over-activeness is associated with a deadly form of brain cancer, and the article ends with an open question from an expert if it could be modulated to not have this adverse effect.

The next step is probably figuring out the tricky balance between these two ends.