Really I don't know about JS Hell, but C++ compilers aren't slow because nobody has tried to speed them up, rather the nature of C++ is that it is slow to compile. Every so often somebody rage quits C++ and starts a language like Go because of this.
The real data point is that Clojurescript is only slightly slower to execute than real Clojure, but takes two orders of magnitude more time to compile.
He's right though that people have to move on past Electron. Lately I have been building applications in Python/tkinter and I still can't get over how fast it is on both my mac and PC both to start up and when running. There is none of the "spend 30 seconds watching a splash screen" that we're are accustomed to with advanced applications in Java and C++ (eg. PyCharm and Photoshop)
Another thing that impresses me is the size and speed of small GUI applications written in C for Windows such as this little utility:
https://docs.microsoft.com/en-us/sysinternals/downloads/disk...
I think MacOS is also part of the problem. Lately I added a new keyboard to my Mac and I thought I was having Bluetooth problems but the main reason it was unresponsive was that the spellchecking baked into the OS would cause keyboard input to lock up for a few seconds periodically.
Later on I noticed that web browsers on Mac OS (Safari/Firefox/Chrome) seem to "go to lunch" and not respond to mouse clicks for 5 seconds every so often. I imagine this impacts Electron apps.
I think people have been "frog boiled" into expecting computers to be slow.