It is indeed helpful. Thanks! I get often confused by the other semantic tags like article, section etc
On the other hand, nav and banner (among others) are types of landmarks. It's nice to have those, but the one that screen reader users will want all the time is main.
The tricky thing about when you're talking about screen readers is that you now have to take into account browser support AND screen reader support, which can sometimes multiply the amount of test cases for things.