> Cross-breeding allows nature to combine things that fit together in all of the right place

I feel like this is putting too much faith in "natural" methodologies.

Eg, who's to say a cross breeding solution is less dangerous than a GM solution?

If the concern is that it may take 50 years to know the GM is bad, why are we assuming the non-GM is good now? You could say that people have been cross breading for many many generations, but i'm unsure why we'd know that one cross breed being safe means all crossbreeds are safe. I'm not inherently defending GM. I'm attacking the notion that man made tricks like cross breeding are inherently safe.