All other virtualization software runs fine on Windows Home.
- "One of the key enhancements we have made for Windows Sandbox is the ability to use a copy of the Windows 10 installed on your computer, instead of downloading a new VHD image as you would have to do with an ordinary virtual machine." - "we also allow Windows sandbox to use the same physical memory pages as the host for operating system binaries via a technology we refer to as “direct map”" - "More recently, Microsoft has worked with our graphics ecosystem partners to integrate modern graphics virtualization capabilities directly into DirectX and WDDM, the driver model used by display drivers on Windows." (Note: it also works with OpenGL nowadays too)
Maybe you can achieve your workflow needs from Home + free 3rd party virtualization software but if you don't see anything special I'd recommend reading the article more carefully.