How many calories are you expending? The answer is: It depends. How (warm|cold) is it? What's your average body temperature? How much clothing do you wear? What's your genetic makeup? Doing a lot of thinking? What's your current exercise regimen? Is your body in state X where it burns (more|less) calories than state Y? Are you sick?
Calories in and calories out sounds good on paper and seem obvious to an engineers mind, but if you can't tell how many calories are involved on each side of the equation, it's a meaningless measure.