I wonder this too. My guess is it could be similar to programming-- there's times when it's just me and my computer-- everything else is a distraction. Other times though, I'm working with others, asking questions, helping people or socializing. I have friends at places where they have offices, and I work on an open-office space: we each like and dislike different aspects of our respective setup.
From my experience in college (anecdotal observations), there's professors who seem to spend a lot of time working with others. They were solving problems with grad-students or at meetings-- though there's some I always found alone in their offices too. I'm sure this varies by person and by field, but I'd be interested in knowing if the open office is working for the faculty here.