The issue is that a neti pot is that you're intentionally putting water deep into the sinus cavities. This amoeba is exactly why they tell you to only use sterilized water in a neti pot and to clean and sterilize your neti pot regularly.
[0]: https://www.theepochtimes.com/surfer-dies-from-brain-eating-...
[1]: https://www.dailymail.co.uk/news/article-2392917/Hope-Kali-H...
[2]: https://www.nbcnews.com/health/health-news/brain-eating-amoe...
> Naegleria fowleri infects people when water containing the ameba enters the body through the nose. This typically occurs when people go swimming or diving in warm freshwater places, like lakes and rivers.
Does it mean sea water is safe or at least safer?
https://www.iflscience.com/brain/brain-eating-amoeba-kicks-f...
As for the ocean, its salinity prevents that kind of amœba from even being present.
https://www.kolotv.com/content/news/Child-dies-from-brain-ea...
https://www.allaboutvision.com/contacts/acanthamoeba-keratit...
If you're a contact lens wearer, you should be careful using them while swimming or rinsing them with tap water. A hydrogen peroxide cleaner like Clear Care will help kill amoebas.