Interestingly this will make it harder to grow high quality outdoor and even indoor (pollination risk rising; one reason it became relatively easy to grow high-quality outdoor is it the government ensured there were no males in vicinity!)
I recently learned from Narcos:Mexico that when drug cartels first created a female breed, they moved to cultivate it in the middle of a desert to ensure no cross-pollination.
Just an FYI, cannabis sativa has been grown for thousands of years.