If a 20-year old had the skin and cardiovascular system of a high functioning 60 year old, they would be in and out of the hospital, and undergoing serious therapy to prevent a predicted death in their 30s.
Rejuvenation therapies are best applied in advance, when the damage of aging is low. Don't play the game of saying that a 60-something who can walk around without a cane is just fine. They are not just fine. They are candidates for every form of therapy we can build that repairs the molecular damage of aging.
Every 60-year should be taking senolytics today, right now, for example. Their good-for-a-60-year-old metrics would be greatly improved by doing so.