I've noticed that as I get older, I generally get sick less often and in less severity. This is probably because I have been exposed to so many variants through getting sick so often when I was young and also getting the flu shots yearly for the past 25 years. Seems like I've just built up a bit of a strong defense because my body's database of seen viruses is fairly long.
That all being said, I (and we) still need to be smart about reacting to an infection. It seems that reacting quickly with the cold meds can help the body react to the exponential growth of the infection. This seems to give the body time to react and catch up with the defenses. Waiting until the symptoms are the worst to take meds is the wrong process. [1]