I'd guess they mean "use the system package manager", given that they talk about patches not in upstream?
Ah, I see, thanks. Still, that's a non-starter. Many of the packages I use are not available through any system package manager, and it would preclude using virtualenvs.
OTOH, I desperately want to move away from Python.
Could you let us know which packages you're trying to install via PIP that cause you issues?