Chrome I can at least disable CORS via the command line, and Safari does it best by putting it in a Developer menu that I can easily toggle.
Firefox's dev tools also seem to still be behind — I haven't seen a good way to inspect WebSocket frames, for instance.
I would really prefer to use Firefox due to Mozzila's stances on privacy, especially in contrast to Google; however, I have to use the tool that lets me actually get work done.