Furthermore, what is the purpose of Malvertising filter list by Disconnect, Malware Domain List, Malware domains, in uBlock Origin if they can't protect the user from malwares?
Avast, Avira, Bitdefender, CheckPoint SandBlast Agent, Malwarebytes, McAfee, Panda, Windows Defender,... All are extensions made to enhance the effectiveness of it's own security suite.
uBlock is just a content-blocker.
uBlock Origin is NOT an "ad blocker": it is a wide-spectrum blocker -- which happens to be able to function as a mere "ad blocker". The default behavior of uBlock Origin when newly installed is to block ads, trackers and malware sites -- through EasyList, EasyPrivacy, Peter Lowe’s ad/tracking/malware servers, various lists of malware sites, and uBlock Origin's own filter lists.
However, I assume that most people still use it mainly for blocking ads. And for that it is excellent.