http://aliciapatterson.org/APF0704/Johnson/Johnson.html
In both cases, using the GA allowed a player to more comprehensively search the opportunity space created by the game designers than the designers did during design and play testing.
Really awesome stuff, though it sets up an intriguing arm's race between the game designers who can patch and Nerf elements to eliminate unbalanced strategies and the players who then explore the new rule set.