Business startup by necessity has gone down. It's much easier to get hired by an international company in a niche field and work from home now, so people no longer are required to start a business to work in the field of their choice
It's more difficult to start something really innovative, related to the slowdown of Moore's Law
It's more difficult to start a business in an established field, as licensing laws have come to cover so much more of the landscape. You can no longer just decide to become a barber and hang out your shingle.