We do recommend using keyed elements (indexing using <tag@{mykey}> syntax) for large lists. It includes automatic pruning of cached unmounted elements etc if you reach a certain threshold of unique memoized nodes within a list over time).
It performs a lot better for a platform like scrimba at least - which is pretty dynamic.
I just hope other frameworks will adopt our approach, because it really is a huge step forward compared to most of what is out there today.