Virus Explorer – visualize and compare viruses in 3D models
hhmi.org
hhmi.org
It looks like they've tried to get surface density of proteins right, but I'd love to know if those densities are about right. This is all important for understanding viral receptor binding, and the importance of multi-valent interactions.
In fact, viruses like HIV and influenza are very much like compact computer programs. Every part of them has a particular purpose and interfaces with the host organism's mechanisms. It exploits the host and forces it to reproduce the virus. HIV's genome is even compressed using overlapping reading frames. It almost seems like it must have been designed.
One really cool part of the virus reproduction is that it must get the host to both reproduce and express its genome (ie. make proteins out of it). These things happen at completely different parts of the cell, yet somehow enough of the reproduced genomes end up in perfectly formed virions that the whole thing keeps working. Fascinating.