I'd love to have a Linux distro with the frontend of Elementary OS and the backend of Nixos. And I say that as a Microsoft employee. Are there efforts to make Nixos grandma-worthy? Or are the only pretty distros all reskins of Ubuntu?
I'm actively trying to build some cool things with Nix/NixOS and then write up a series of blog posts. Several recent discussions on the Discourse and at NixCon have been focused around Nix/NixOS user experience, at least.
I've recently been building a package set of tip builds of Wayland stuff (sway, screenshot/screenrecord/notification utilities), including instructions for using them on Ubuntu via Nix. I'm also building out a set of packages and modules for Kube/Containerd/Kata-Containers for perfectly repeatable offline-first clusters. I think these two projects can be leveraged to evangelize Nix and NixOS nicely, and dovetails into UX efforts as I build my list of rough spots and fix a number of issues in nixpkgs and random OSS projects along the way.
Also, Gnome-Shell and KDE work perfectly in NixOS anyway, and can be easily made to look just like they do on any other distro... I just recently switched to Sway, coming from KDE (~1.5 years) after GNOME (6+ years?). Not any significant visual differences than when I was using Arch Linux.
Having the ability to configure a beautiful-by-default GUI for NixOS makes it much more likely that I can maintain machines for my family with low time effort, remotely.
At the moment it seems that a lot of NixOS users (including me) prefer a keyboard-centric window manager to a full desktop environment, but obviously (well I think it's obvious, anyway) there's a place for Pantheon on NixOS too. A big place, I should think.
However my main desktop these days is a bog standard Win10... probably showing my age that I can't be bothered to tinker round with it anymore.