The current POTUS made a campaign promise that he would only allow a regulation to be added if two more were eliminated. This is asinine. If there are unnecessary regulations, get rid of them. Get rid of them because they're unnecessary or counterproductive, not because they fall into a category of legislation referred to as "regulations". Losing a regulation isn't an inherently good thing any more than gaining one is an inherently bad thing. The only thing that matters is whether or not it's a net positive, and that's specific to each regulation. It's like saying, "there's too many laws! We need to get rid of some laws!", and proceeding to randomly choose laws to get rid of until numberOfLaws <= totallyArbitraryMaximumLawCountThatSomeoneMadeUp.
Fewer, well-chosen regulations with very strong penalties that easily pay for strict enforcement activity - that's much rarer; and I'm cynical enough about how gets to influence lawmakers, that I know why that is.
How about a largely deregulated area where you can mix housing and business zoning. Like we use to with downtowns. At the same time get rid of the caps on building height. Tokyo has tall buildings and earthquakes. Allow SF to modernize. A 60 story apartment building neutralize the cost of the property.
Another option is to make SF a stronghold for the rich. Nothing wrong with that either. Push the poor out to locations they can afford.
Few will die in either scenario.