Good questions. How many sales I need per month to be profitable depends on how much I spend on advertising, which is my main expense. If I can find a better advertising method (I'm currently using Trada.com for PPC), then I will be able to reach profitability faster.
As far as maintaining margins as I grow, there should not be a huge problem with dropping margins, unless I have to drop my price point. I will be hiring an account manager/customer service person once I have enough sales per month to make it worth it.
Perhaps I have missed some crucial details - please feel free to point these out.
Thanks!