No-one know why Ms Giese survived, but the Milwaukee protocol does not seem to have been the reason. Or if it was, it is not repeatable on other patients.
[1] https://www.cambridge.org/core/journals/canadian-journal-of-...
It's a difficult trade-off for a lot of high risk medical interventions to judge the relative worth of the potential chance of survival vs. that last remaining time, and it's certainly not a choice we can objectively make on behalf of other people.
In this case it's not certain the protocol have helped any patients. If it did help, then the success rate is so low that there are ethical issues with overselling the potential vs. giving people that extra time together.
If a patient wants to try, I'd be all for giving them that choice. But there's a big gap from letting a patient ask for something and promoting it as the recommended course of action without evidence of any efficacy.
An NCBI article claims 13: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947331/
It also notes the deaths of at least two of the "known survivors", that others received the PEP vaccine either completely or partially, and that one survivor likely didn't have rabies at all due to no anti-bodies being found.
That leaves just the original case in 2004 where someone survived without vaccine and received the MP.
https://www.sciencedirect.com/science/article/pii/S016635421...
If I were there patient and my options were medicated coma that possibly has an 8% chance of healing me and possibly has no benefit, I'd prefer that to the excruciating death by rabies I'd be facing otherwise.
https://www.cambridge.org/core/journals/canadian-journal-of-...
So where does 13 come from?
Several others had completed most or all of the PEP treatments, and it's not clear if the MP had anything to do with their survival, given other patients have survived without MP in similar circumstances.
Notably:
> Prior to 2004, there were only five documented human survivors, all of whom had received the PEP, albeit incomplete or late [5] > In 2004, the first survivor without PEP was reported after this individual had undergone the MP. However, the use of the MP did not increase survival in subsequent cases [6]. Our patient was managed with aggressive supportive care without the MP or steroids. Our patient survived the acute phase of rabies encephalitis and was discharged after five months of intensive nursing care in the hospital.
And:
> Out of the seven reported rabies survivors until 2008, only the index case that used the MP did not receive PEP. Rabies virus was detected in only one case in all of the others that were diagnosed using only the rabies antibody [9]. Our case was diagnosed using both the rabies antibody and highly specific rabies antigen detection tests.
The article points out a number of confounding factors that makes it hard to determine what saved the patient, including potential effects of use of PEP even if unsuccessful in stopping the disease completely (e.g. note that the virus itself was only found in one of the cases of survivors discussed by this article), the high level of other interventions to manage the disease, as well as the potential for genetic variations and the possibility that some of them didn't have Rabies in the first case
Treatment success rates: Vaccination: ~100% PEP: ~100% MP: ~8%
So MP provides a slightly less than 1/10 chance for life when the patient would face otherwise certain death.
You might find this interesting: http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2017...