My only counterpoint is that I and many other "laymen" (as apparently we're referred to?) can't be expected to appreciate your work if you can't explain it.
It's not like genetics is the only field that struggles with this. I'm primarily a web developer and still remember the 10+ years of trying to explain to people why "The Web" was an important technology that would radically impact all of our lives. I still remember the bubble. I still remember being told this was a dead field. Where are those people now?
I remember how dismissive people were about mobile apps, too.
The same challenge applies to AI, blockchain, virtual/augmented reality, etc.
As a non-scientist, I struggle to explain to people why it's important that we increase our funding and support for all of the sciences. It's hard to appreciate how seemingly "useless" discoveries combine with other "useless" discoveries to give us the amazing advances in technology and medicine that we have today.
BUT, we have to try.
And when some "layman" dares to ask about the meaning of such-and-such a discovery, maybe take a deep breath, recognize we don't all have you incredible knowledge about this topic, and appreciate that someone is expressing interest in what you do, in the only terms they have available to them.
All of which was a long-winded way of saying: All I know about CRISPR is what I read in relatively mainstream publications. Help me out. Or don't. Your call, really.