I just returned from my first trip to Chicago, and noticed some related things when comparing to other large cities I'm familiar with.
Related to honking and street noise, another factor I noticed is a high number of curbs where parking is simply not allowed. This streamlines traffic in some ways, as people aren't fighting over spaces or waiting for someone to back in slowly. Although, there was a lot of "hazard parking" where people just stopped where they weren't supposed to. A lot of the honking I witnessed was due to freight/waste vehicles blocking an entire street (2-4 lanes) so they could back into a dock or service area in the middle of a block.
Downtown at night seemed eerily quiet, although there were a good number of people. I think several factors applied here, when compared with SF... Chicago has been built to handle the vast crowds from events and conventions that swarm the city. When that isn't happening, there is comparatively more room for people, so it's wide sidewalks aren't as crowded. Also, being built to withstand harsh winters, I imagine there is better thermal insulation that also acts as decent audio insulation (plus a lot is happening under the street level!). I was right outside blues and jazz clubs where you couldn't actually hear that anything was going on inside (this makes me laugh when compared to visiting Nashville for the first time earlier in the year).
It also seemed that the contention between drivers, cyclists, and pedestrians is more severe even than SF, where I saw several interactions that seemed more like a macho game of "chicken".