> The most common adverse reactions in patients taking Xofluza included diarrhea and bronchitis.
I wish the article listed the frequency or likelihood of getting these reactions. Given the choice between flu and bronchitis, I'll take the flu.
I wish the article listed the frequency or likelihood of getting these reactions. Given the choice between flu and bronchitis, I'll take the flu.
Adverse event - Xofluza(%) - Placebo(%)
Diarrhea - 3% - 5% [higher in placebo]
Bronchitis - 2% - 4% [higher in placebo]
The FDA requires that the manufacturer list the most common adverse events, even if they are unrelated to the drug in question.
[1]https://www.gene.com/download/pdf/xofluza_prescribing.pdf
https://www.scientificamerican.com/article/placebo-effect-gr...
I don't even bother with the doctor anymore (unless I have a fever) because I'm not interested in the codeine and I can just buy Primatene (ephedrine + guaifenesin) over the counter. Both my doctor and a pharmacist have admitted they could do no better.
How often do you get the flu (actual flu, not a bad cold) and not have a fever? I've only had the flu once in my life (30-something years), and it was like being hit by a bus, having said bus park on your body, and having said bus catch on fire and slowly burn.
I've had pneumonia at least twice as an adolescent, but which went untreated for awhile because it was typical for me to have prolonged coughing and lethargy after a respiratory illness. So while I'll treat my own bronchitis, I have to be mindful that the bronchitis could be secondary, or could have resulted in an infection.
I would be more curious about how well does it play together with something like ambroxol hydrochloride - I used to get bronchitis as a complication every time I get cold in the past but as soon as I've discovered ambroxol hydrochloride I've forgotten about ever having bronchitis as a bad dream.