Wow, so sad. Like Jobs, he dying young is a loss to humanity.
Separately that OS that made Microsoft as everyone knows they bought from another company.
A space company, half a billion into brain research, tens of millions more in other fields, environment efforts, multiple sports teams, cultural investments, etc. That's a fair loss, and I think the first few qualify adding "to humanity" as well.
Donated $2 billion in his lifetime.