Some of the heavyweight ones are nice as far as human readability goes. Consider the AutoSlugField (in Django). Say you have an object, Item(name='Phillip Lim Pleated printed silk-chiffon dress', description='...).
Which link is less scary?
http://secret-project/item/phillip-lim-pleated-printed-silk-...
or
http://secret-project/item/47a61d7c-dde1-11df-ba19-0026c72a6...