you all should install uMatrix webextension and stop just "wishing". the future is now :)
That said, uMatrix, from what I remember, uses the webRequest api which does work from urls. So if you know JS, you can always create an extension and add your own filter.
it will show a checkered pattern with a link to open the frame in another window. so you don't even have to whitelist sites or anything. if you care about the frame, like for a embedded video, just open it on its own tab with a single click