It's very unlikely that a drone would hit an aircraft wing at combined speed that high - but certainly possible. I'd be more concerned about one going through a windshield at a slower speed and damaging the pilot.

In US airspace, there's a speed limit of 250 knots (around 290mph) below 10,000 feet. Most light aircraft cruise significantly slower (~140 mph for a Cessna 172) and closer to the ground, whether on approach, takeoff, or other, most aircraft are likely to be going slower than that - so this test is at the high end of that range, even if you add the maximum speed of a DJI Phantom (~40mph) and assume it's flying directly at the aircraft.