Booking.com [2] uses HAProxy for edge delivery over other software load balancers.
Github [3][4] has used it to mitigate DDoS attacks and StackOverflow [5] has used it to detect and protect against bot threats.
Finally, phk, the author of Varnish states [6] (in regards to implementing SSL/TLS): “When I look at something like Willy Tarreau's HAProxy I have a hard time to see any significant opportunity for improvement.”
[1] https://www.haproxy.org/#secu
[2] https://events.static.linuxfound.org/sites/events/files/slid...
[3] https://www.youtube.com/watch?v=xxs7CoLMXt8
[4] https://githubengineering.com/glb-part-2-haproxy-zero-downti...
[5] https://events.static.linuxfound.org/sites/events/files/slid...