I'd go so far as to ask: "can this candidate learn to do the job?". In our recent job postings, I've started adding a specific paragraph after the desired qualifications stating more or less "if you don't tick all the boxes above but are motivated to learn and grow, please apply. We'll teach you what you need to do the job"
> 2. Will this candidate be motivated?
This. Even more than question 1. I've had a lot of good surprises with motivated candidates who didn't have all the expected qualifications. Some of my best hires were people whose CV didn't line up with what I was looking for but who demonstrated impressive motivation to get the job. On the other hand, I've often been disappointed with "perfect" candidates who didn't have the right mind-frame for the job. (Note: I'm not saying I'm expecting slavish devotion and "giving it 200%" every day of the week. But if your personal, intrinsic motivations don't align with the job's responsibilities, it won't work).
> 3. Will this candidate get along with coworkers?
Duh. But also, how do you actually test objectively for this without introducing bias? And how do you insure you're not creating a monoculture that will eventually harden into navel-gazing and dogma? I'm really of two minds on this topic.
> 4. What this candidate will be in three, six, twelve months from now?
Related to the rephrasing of 1. Can the candidate learn and grow? And will we provide the right environment for them to grow?
One of my favorite quotes is from an ex-manager who hired me when I was far from ticking all the boxes on the job description. "If you hire someone who has all the necessary qualifications for the job, they'll be bored in 6 months."