It's incredibly humid the entire year. Close to 100% humidity and 100 degrees F quite often in the middle of the day. April through November is just hot as heck.
You are hot and sweaty...and stay hot and sweaty until you take a shower and dry off. I see people walking around in suits downtown and I can't understand how they manage it. Getting into your car is a task because you're essentially hopping in an oven.
Additionally, today is the first "nice day" in a while and its's still 90 F with 60% humidity. It's almost October. We don't really have a fall, which is what I loved about living further north in Atlanta. I'm exhausted by it by the time August ends and this will last into November.
The strangest part is that the humidity makes cold nights feel even colder than dryer places. So 45F in Tampa is crazy cold due to the moisture in the air. It doesn't help that we're not geared up for those 10 nights per year either. I noticed this when I spent time in CO. I want to go for a run at 45F in Denver!
The only other major gripes I have is that our transportation and the way our downtown has developed hasn't worked. Urban sprawl hurt us quite a bit with the former.
But(!), there are benefits. * I can easily get away with wearing shorts for nearly the entire year. I go to meetings in shorts and it's great. * Rent is _very_ reasonable. * Lots of outdoor things to do: our Riverwalk downtown is amazing to bike/walk/run on. * We have some quality food and FL loves beer, so we have some nice breweries beyond Cigar City.
Due to the heat, I want to spend some of each year up north. It's just too much for me.