Spammers Use The Human Touch To Avoid CAPTCHA
npr.org
npr.org
Another option is to give english-language instructions on how to fill out the CAPTCHA. For example, "type the characters in reverse order".
You could make these more complex, like "remove the third, fourth, and seventh character and then unscramble the remaining characters to spell the name of the object pictured to the side".
As the article mentioned, this will not 100% stop spammers, but it will make it a bit more costly to them, probably stopping those whose margins can't handle the financial hit.