On the other hand, 5-Meo-DMT (5-Methoxy-N,N-Dimethyltryptamine), comes in the form of an organic lab-produced extract, or the Bufo Alvarius venom, takes it to a completely different level of non-duality and complete and utter shattering of your ego (temporarily of course, for about 20 minutes). Someone named Albert Most discovered this bizarre compound a few decades back by smoking the venom from the glands of a Sonoran Desert toad somewhere in New Mexico if I recall correctly. I haven't tried it myself but going down a rabbit hole of reports and practitioners on YouTube is in and of itself a profound trip: https://youtu.be/PQctOMSmBuk . EDIT: Here is the piece Vice did on Albert Most: https://www.youtube.com/watch?v=00jbzI4bcUw