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Comment by breatheoften | Hacker News Reader

I just associate DMT with nausea — and have no desire to repeat that pain. I did an ayuasca ceremony and only managed to drink one dose (you are encouraged to drink a lot more) — but my body felt so awful and all the evidence suggested the pretty obvious cause that there was no part of me that wanted to drink more and I felt completely fine with my decision to stop.

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You probably know this but for the benefit of others: Monoamine oxidase inhibitors will make you feel pretty awful without paying close attention to diet for several days.

Even following a dieta won't necessarily keep you from having a physically uncomfortable time with ayahuasca! But it's virtually guaranteed if you do not.

ayuasca and smoked DMT are too very different experiences.

Yes. And the article didn't make that clear enough. The biological lifetime of DMT is very short, because there are enzymes (monoamine oxidase aka MAO) in many tissues. So the effects last 15-30 minutes. But ayahuasca includes MAO inhibitors, so the effects can last for many hours. And it's mainly the MAO inhibitors that make users feel ill.

Changa includes rima (hamalas from b.capii) and lasts around an hour if good. And No nausia or effect from food.

Hey, thanks for that!

I used to have a book about ayahusca-like formulations, using plants from various continents. But I've forgotten the name. Basically, many plants contain DMT, and many others contain MAO inhibitors. Also, I believe that one can combine some MAO inhibiting antidepressants, such as selegiline, with DMT.

Did you not expect that going in? Or it was worse than anticipated?

I had the understanding beforehand — but the pain completely overwhelmed the amount of curiosity I had for the experience — brain said don’t drink more - and after that it was just sitting in a painful body until recovery ...

Try changa/ smoke dmt. Its without the nausia, shorter and more intense.

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