BTW, it really exists https://www.ipv6buddy.com/ (but does not have +, - and other traditional numpad keys).
Healthier wrist positions should take precedence?
If you're doing numerical data entry the keypad is a star. If you're doing programming/writing, stick to the number row.
But even if we ignore that omission the lack of F keys is a complete deal breaker. There's a reason I won't touch the new Macbook Pros with Touchbar, this is worse than that.
Its purpose is to give everyone what they need, but without needing them to have a bajillion different physical interfaces on their desk/s. You want F-keys, someone else wants a numpad, another wants Logitech's G-keys, et cetera, et cetera, et cetera. The UHK says enough. You can do it all on one set of buttons. It may not be your style, but saying it's lacking F-keys is disingenuous.
Absolutely. I will never buy a keyboard with an attached numpad because it splays my mousing hand way out to the right in an very awkward manner. That is one of the reasons I bought the UHK.
One of the really cool features of the UHK I was surprised to discover after I received it is that it can control your mouse cursor and right/left/middle buttons by using the Mod keys and h/j/k/l keys. Yes, I'm sure you can download some utility that enables this on any keyboard but it's nice to have it built into the firmware.