I think the best one so far was Github Cofounder Tom Preston-Werner's talk. Almost every sentence of his was a gem, and the fact that he had bootstrapped both his startups made it even more interesting!
I agree that Tom Preston-Werner had some great advice especially about "bootstrapping while working your fulltime job to pay the bills."
Watching Adam D'Angelo was a bit painful, he was really nervous and unfortunately due to streaming issues it seemed like some of the bad moments were showed over and over -- that said, the bit of his talk that stood out was "having a good reputation helps open doors". I didn't get to see his whole talk, hopefully he expanded upon how to build that good reputation...