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On the other hand there has not been a single nuclear explosion within city limits since those signs went up.

Well, at least that's dangerous.

That wasn't about resident safety, it was about a moral position against war. IIRC, those went up in the 80s when residents wanted to ensure that Lawrence Berkeley National Laboratory couldn't legally do the kind of weapons-directed research that Lawrence Livermore National Laboratory did.

Don’t they have a research reactor on campus?

The reactor under Cory hall was decommission years ago and it's the CS department now.