Crohn's is another inflammatory disease that has long been suspected by some researchers to be infectious. The company RedHill Biopharma just showed that a combination of generic antibiotics could be as effective as Humira, the highest gross-selling drug in the world, at treating the condition.
https://www.redhillbio.com/RedHill/Templates/showpage.asp?DB...
I keep seeing news about severe impacts of chronic infections that we aren't good at testing for, and aren't good at treating. Gut microbes that cause cancer, only just recently deciding that HPV's cancer risk to men was significant, and chronic Lyme disease are some examples.
This article cites the historic example of peptic ulcers, which the medical community didn't believe were caused by an infection, until after Barry Marshall infected himself with H. pylori in 1984, developed disease, and treated himself for it with antibiotics. Marshall and his partner won a Nobel Prize for this work.