It may also depends on how you get them. For example somebody told me that turmeric helps with joint inflammation. Bought some turmeric capsules and they did nothing. But then I used it in cooking and it definitely makes a difference for my joint pain. It comes back while traveling and I don't get turmeric. But as soon as I get home and eat my own food the joint pain gets better. It also gets worse when I stop using turmeric in my own cooking for a while.