What I find a big shortcoming from CMake is that it does not have support for building for multiple architectures at once.

https://cmake.org/pipermail/cmake-developers/2014-September/...

Quote: "The fundamental problem with supporting multiple architectures is that pretty much all of CMake is designed to support one architecture at a time. Modules/*, CMakeCache.txt, etc. are all built around only finding, using, and building one artifact per library (OS X universal binaries work with multiple architectures because they are still only one file). I think even your "toolchain scope" approach would end up being used in practice to wrap the entire CMakeLists.txt file."