I'm woken up by screaming drunk tourists as they come home at 3am on a Tuesday night. There are constantly people clattering suitcases up the stairs at all hours. People smoke inside the common areas instead of on the street. Of course, just generally feeling like you live in an illegal hotel is horrible. We're looking to move.
Then again, I have reservations for two AirBnBs next week on holiday in another part of the country. The difference is we have booked entire houses in the countryside, not city-centre flats. AirBnB is not inherently evil, but strict and enforced controls are definitely necessary in cities.
I love AirBnB as a customer, but hate it as a resident.