MDMA, when I used it, was always combined with dancing or walking or physical activity. I also always had a coming down which had a bottom peak a few days after (the infamous Tuesday dip). With psilocybin I had not much of a coming down, at worst a headache the day after. With MDMA though, the coming down additionally had my mood being down as well. I become agitated and inward, very much in contrast to the peak and moderate upper effect (there are some movies which portrait this, such as the movie Human Traffic [1]). Then again, this is anecdotal, and I am very sensitive to drugs in general, especially the contrasts (alcohol, beer makes me often tired, MDMA, SSRIs, amphetamine). The reason for that might very well be related to ASD, I do not know for sure though. I just know that I do have ASD. But because I have ASD, my anecdotal experience isn't typical in this case. However the Tuesday dip is widely known among MDMA users.