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Comment by simonsaidit | Hacker News Reader

Yes but it’s also pretty common to get into this regularly and soon after what you get one evening you have to give back some weeks later unless you then take all sorts of other drugs to compensate for that. I’ve seen the therapeutic effects up close and they are powerful but they are sadly short lived and hard to manage.

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All advice I've seen regarding the substance is to not take it more than once every 3 months. I think people just need to realize it really isn't a party drug you can take every or every other weekend. Not only will tolerance build very rapidly, but you're exposing your brain to excessive oxidative stress and overheating, and are likely causing serotonergic neurotoxicity (even if you take it with all the recommended supplements).

It needs to be treated like a rare, therapeutic, and special vacation, not something you take whenever you want to have fun.

yup. but young people in a culture where its quite common to do this every weekend are in a big risk not to follow that advice though.

The MAPS studies tell a different story here, only a couple sessions and over a year later a large majority of the subjects were still symptom free or greatly reduced

My personal studies tell Otherwise... and those studies probably doesnt consider how easy it is to self medicate and get the oppersite effect. It Works Well but its a temp fix and its hard to handle yourself Especially if you are Young abd part of a culture that uses this recretional.

Where have you published your studies?

They are personal ;) luckily I now don’t take everything I read for truth and had the guts to look at the risk/benefit in person. Few who ever did studies had any real exposure to what they write about or have the insight to get near the relevant data to make a proper study. First hand experience beats that anyday and having seen more than most I can not recommend any recreational drugs perhaps more that once but keeping it to that is insanely difficult so I’d say you have to be in a specific pet if your life to even try. By I regard Changa as medicine that few would ever use recreational but it’s also not for everyone.

Yeah, all drugs can have big negative impacts on people’s lives if not taken in moderation. This is true of legal recreational drugs like alcohol, and pharmaceuticals like opioid painkillers. But most people use these drugs responsibly.

I think if MDMA really does work great for PTSD in therapeutic settings, it’d be a worthwhile treatment, even though some percentage of patients would abuse it.

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