Pros & cons of IDN ccTLD vs .com for startups e.g. disk.io vs diskio.com?

Does anyone have any thoughts on the relative merits of international country code top-level domains (.io, .gg, .ws etc) vs Plain 'ole .com for startups e.g. disk.io vs diskio.com (particularly since it seems possible to get 'clever' IDN ccTLD names that form a single word relatively easily, whereas .com is more crowded)? I imagine in non-technical niches .com rules the roost, but I have no data to back that up. Also if I've already settled on my 'brand' and want to get keyword-rich domains for landing pages do off-beat TLDs work there too?