On the melatonin I would add that studies have shown negligible increase in effectiveness over 0.3mg. Yes, most pharma stores offer only 3mg and above, but that seems to be wrong.
Personally I've only taken melatonin when I most needed it, and then gave up on it. You should try giving it up, too, unless you really can't do without it.
You should check the vitamin D level, too, whenever you do your next blood test.
As for curcumin, the Longvida formula seems to be most effective. I can't say I've noticed any effects from it myself, but I haven't taken it daily, and I've also read that you need to take curcumin for 2+ weeks to see the effects.
https://www.turmericforhealth.com/curcumin-benefits-and-dosa...