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Not for some games, where low settings are used on purpose. The CPU is the bottleneck in those cases. cough Overwatch cough.

But if your budget is limited, it probably makes sense to go with an AMD CPU if it enables splurging on the GPU.

I play Overwatch at max settings (on a 2K screen) and my FX8370E + RX580 works very fine with it.

I doubt that hardware at that resolution on max settings is hitting much more than 60fps though - a lot of people have 144hz displays.